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pfizer vaccine serum  (Pfizer Inc)

 
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    Pfizer Inc pfizer vaccine serum
    Pfizer Vaccine Serum, supplied by Pfizer Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pfizer vaccine serum/product/Pfizer Inc
    Average 90 stars, based on 1 article reviews
    pfizer vaccine serum - by Bioz Stars, 2026-04
    90/100 stars

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    Pseudoviral neutralization assays of BA.2.75 by vaccine and BA.1, BA.2, and BA.4/5 immune serum (A and B) IC50 values for the indicated viruses using serum obtained from vaccinees 28 days following their third dose of vaccine (A) Pfizer <t>BNT162b2</t> (n = 22) or (B) AstraZeneca AZD AZD1222 (n = 41). (C–E) Serum from volunteers suffering vaccine breakthrough BA.1 (n = 16), BA.2 (n = 23), or BA.4/5 (n = 11) infections. (F) IC50 values for single RBD point mutations inserted into the BA.2 pseudovirus using Pfizer BNT162b2 serum (n = 22). Geometric mean titers are shown above each column. The Wilcoxon matched-pairs signed rank test was used for the analysis and two-tailed p values were calculated. See also <xref ref-type=Table S3 . " width="250" height="auto" />
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    Pseudoviral neutralization assays of BA.2.75 by vaccine and BA.1, BA.2, and BA.4/5 immune serum (A and B) IC50 values for the indicated viruses using serum obtained from vaccinees 28 days following their third dose of vaccine (A) Pfizer BNT162b2 (n = 22) or (B) AstraZeneca AZD AZD1222 (n = 41). (C–E) Serum from volunteers suffering vaccine breakthrough BA.1 (n = 16), BA.2 (n = 23), or BA.4/5 (n = 11) infections. (F) IC50 values for single RBD point mutations inserted into the BA.2 pseudovirus using Pfizer BNT162b2 serum (n = 22). Geometric mean titers are shown above each column. The Wilcoxon matched-pairs signed rank test was used for the analysis and two-tailed p values were calculated. See also <xref ref-type=Table S3 . " width="100%" height="100%">

    Journal: Cell Reports

    Article Title: A delicate balance between antibody evasion and ACE2 affinity for Omicron BA.2.75

    doi: 10.1016/j.celrep.2022.111903

    Figure Lengend Snippet: Pseudoviral neutralization assays of BA.2.75 by vaccine and BA.1, BA.2, and BA.4/5 immune serum (A and B) IC50 values for the indicated viruses using serum obtained from vaccinees 28 days following their third dose of vaccine (A) Pfizer BNT162b2 (n = 22) or (B) AstraZeneca AZD AZD1222 (n = 41). (C–E) Serum from volunteers suffering vaccine breakthrough BA.1 (n = 16), BA.2 (n = 23), or BA.4/5 (n = 11) infections. (F) IC50 values for single RBD point mutations inserted into the BA.2 pseudovirus using Pfizer BNT162b2 serum (n = 22). Geometric mean titers are shown above each column. The Wilcoxon matched-pairs signed rank test was used for the analysis and two-tailed p values were calculated. See also Table S3 .

    Article Snippet: To understand the effects of the individual mutations in the BA.2.75 RBD, we introduced them individually into the pseudovirus BA.2 background and assayed their neutralization using triple-vaccinated Pfizer BNT162b2 serum ( F).

    Techniques: Neutralization, Two Tailed Test